all MUGEN mice

POMC cre


General Information
MUGEN ID
M193031
Common Line Name
POMC cre
Research Applications Type
TRANSGENIC TOOL
Contact
Berns Anton
Institution
NKI-AVL
Research Applications Comments
Pituitary-cells

Availability
Repository Available Background State Type
NKI-AVL FVB/N live mouse mutant strain

Genetic Background
DNA Origin Targeted Background Host Background Backcrossing Strain Backcrosses
nlsCre: P1 bacteriophage, POMC promoter: rat, Splice and pA signal: SV40 FVB/N FVB FVB >=10

Strain Information
Designation
FVB-Tg(PomcCre)5Brn

Allele & Mutations
Name Symbol Mutation(s)
transgene insertion 5, Anton Berns Tg(PomcCre)5Brn transgenic

Gene(s)
Name Comment Chromosome
transgene insertion 5, Anton Berns not provided yet UN

Handling & Genotyping Instructions
Name Type

Mammalian Phenotype Ontologies
 

References
Name Type Comment
Akagi et al., 1997 Nucleic Acids Res 25(9):1766-73 Webblink Cre-mediated somatic site-specific recombination in mice.

Author's Comments
 
Cre activity is detected in the intermediate lobe of the pituitary, and to a lesser extent in the anterior lobe of the pituitary.