all MUGEN mice

EpoR-Cre


General Information
MUGEN ID
M193047
Common Line Name
EpoR-Cre
Research Applications Type
TRANSGENIC TOOL
Contact
Pfeffer Klaus
Institution
UNIDUESSEL
Research Applications Comments
Germline

Availability
Repository Available Background State Type
UNIDUESSEL BalB/c unknown unknown

Genetic Background
DNA Origin Targeted Background Host Background Backcrossing Strain Backcrosses
EpoR promoter and polyA, murine; eGFP, jellyfish; iCre, bacterial BALB/c-I C57BL/6 BALB/c >=10

Strain Information
Designation
C-Eportm1(EGFP/cre)Uk

Allele & Mutations
Name Symbol Mutation(s)
targeted mutation 1, Ursula Klingmuller Eportm1(EGFP/cre)Uk transgenic, targeted mutation

Gene(s)
Name Comment Chromosome
EpoR-GFPcre not provided yet UN

Handling & Genotyping Instructions
Name Type
Docs
PCR protocol.docFile

Mammalian Phenotype Ontologies
 
MP Term: lethality-embryonic/perinatal>embryonic lethality
PATO Logical Definition: 
 

References
Name Type Comment
Heinrich et al., 2004 Blood 104(3):659-66 Webblink A mouse model for visualization and conditional mutations in the erythroid lineage.

Author's Comments
 
Cre and GFP are solely expressed by erythroid progenitors and recombination of floxed alleles reaches efficiencies close to 100%.