all MUGEN mice

Alb.Stop.Tag, AST (C3H)


General Information
MUGEN ID
M195003
Common Line Name
Alb.Stop.Tag, AST (C3H)
Research Applications Type
MODEL OF HUMAN DISEASE
Contact
Haemmerling Guenter
Institution
DKFZ
Research Applications Comments
Multiple

Availability
Repository Available Background State Type
DKFZ live mouse mutant strain

Genetic Background
DNA Origin Targeted Background Host Background Backcrossing Strain Backcrosses
albumin promoter/enhancer, mouse; stop cassette, ; T antigen (Tag), SV40 viral B6D2F2 B6D2F2 C57Bl6 >=10

Strain Information
Designation
Tg(Alb-TAg)1Gjh

Allele & Mutations
Name Symbol Mutation(s)
transgene insertion 1, Gunter J. Hammerling Tg(Alb-TAg)1Gjh transgenic

Gene(s)
Name Comment Chromosome
transgene insertion 1, Gunter J. Hammerling not provided yet UN

Handling & Genotyping Instructions
Name Type

Mammalian Phenotype Ontologies
 

References
Name Type Comment
Hämmerling Webblink

Author's Comments
 
alb promotor/enhancer and SV40Tag plus floxstop cassette. After cre mediated floxstop deletion Tag oncogene expression is initiated. AST is an inducible mouse model for autochthonous liver tumors. Stahl et al in press Immunol.Letters 2009