all MUGEN mice
Actin-Cre
General Information
MUGEN ID
M199007
Common Line Name
Actin-Cre
Research Applications Type
TRANSGENIC TOOL
Contact
Berns Anton
Institution
NKI-AVL
Research Applications Comments
Germline Deleter
Availability
Repository
Available Background
State
Type
JACKSONS
FVB/N
cryopreserved embryos
mutant strain
Genetic Background
DNA Origin
Targeted Background
Host Background
Backcrossing Strain
Backcrosses
beta-actin promoter, human; cre, P1 bacteriophage
FVB/N
FVB/N
FVB/N
>=10
Strain Information
Designation
JAX ID
FVB/N-Tg(ACTB-cre)2Mrt/J
003376
Allele & Mutations
Name
Symbol
Mutation(s)
transgene insertion 2, Gail R Martin
Tg(ACTB-cre)2Mrt
transgenic
Gene(s)
Name
Comment
Chromosome
transgene insertion 2, Gail R Martin
not provided yet
UN
Handling & Genotyping Instructions
Name
Type
Mammalian Phenotype Ontologies
MP Term:
normal phenotype>
no abnormal phenotype detected
PATO Logical Definition:
References
Name
Type
Comment
Lewandoski et al., 1997 Cold Spring Harb Symp Quant Biol 62:159-68
Webblink
Analysis of Fgf8 gene function in vertebrate development.
Author's Comments
Cre recombinase expressed under the control of a human beta-actin promoter, which is active in all embryonic cells at or before the blastocyst stage. Useful as a "deletor" mouse for virtually any genomic sequence flanked by loxP sites.
