all MUGEN mice

ATX


General Information
MUGEN ID
M201010
Common Line Name
ATX
Research Applications Type
MODEL OF IMMUNE PROCESSES
Contact
Aidinis Vassilis
Institution
FLEMING
Research Applications Comments
No research application specified

Availability
Repository Available Background State Type
FLEMING C57BL/6J live mouse mutant strain

Genetic Background
DNA Origin Targeted Background Host Background Backcrossing Strain Backcrosses
C57BL/6J C57BL/6J C57BL/6J C57BL/6J >=10

Strain Information
Designation JAX ID
B6-Enpp2tm1.1Vart/Flmg 3814720

Allele & Mutations
Name Symbol Mutation(s)
ectonucleotide pyrophosphatase/phosphodiesterase 2; targeted mutation 1.1, Vassilis Aidinis Enpp2tm1.1Vart targeted mutation

Gene(s)
Name Comment Chromosome
ectonucleotide pyrophosphatase/phosphodiesterase 2 not provided yet 15

Handling & Genotyping Instructions
Name Type
Docs
atx_genotyping_protocol.pdfFile

Mammalian Phenotype Ontologies
 
MP Term: lethality-embryonic/perinatal>embryonic lethality>embryonic lethality before turning of embryo
PATO Logical Definition: 
 

References
Name Type Comment

Author's Comments
 
Upon Cre-mediated recombination, exons 1 and 2 together with the neomycin selection cassette were excised to generate the knock-out allele.