all MUGEN mice

P0-Cre


General Information
MUGEN ID
M205003
Common Line Name
P0-Cre
Research Applications Type
TRANSGENIC TOOL
Contact
Berns Anton
Institution
NKI-AVL
Research Applications Comments
Cre mediated expression to Schwann cells.

Availability
Repository Available Background State Type
NKI-AVL FVB/N live mouse mutant strain

Genetic Background
DNA Origin Targeted Background Host Background Backcrossing Strain Backcrosses
Cre:P1-bacteriophage,POMC Promoter,P0 gene:rat, 5'pA:SV40,3'pA and beta-globin:rabbit FVB/N FVB FVB >=10

Strain Information
Designation
FVB-Tg(Mpz-cre)1Brn

Allele & Mutations
Name Symbol Mutation(s)
transgene insertion 1, Anton Berns Tg(Mpz-cre)1Brn transgenic

Gene(s)
Name Comment Chromosome
transgene insertion 1, Anton Berns not provided yet UN

Handling & Genotyping Instructions
Name Type

Mammalian Phenotype Ontologies
 

References
Name Type Comment
Akagi et al., 1997 Nucleic Acids Res 25(9):1766-73 Webblink Cre-mediated somatic site-specific recombination in mice.

Author's Comments
 
Rat P0 gene directs expression of Cre to myelinating Schwann cells. The expression is not universal to these cells.