all MUGEN mice

Cia-NOD


General Information
MUGEN ID
M221012 		Common Line Name
Cia-NOD 		Research Applications Type
MODEL OF IMMUNE PROCESSES
Contact
Holmdahl Rikard 		Institution
ULUND 		Research Applications Comments
MHC class II

Availability
Repository Available Background State Type
ULUND C57BL/10.H2q live mouse major histocompability congenic

Genetic Background
DNA Origin Targeted Background Host Background Backcrossing Strain Backcrosses
NOD.Q B10.Q >=10

Strain Information
Designation
B10.Cg-Cia2NODH2q

Allele & Mutations
Name Symbol Mutation(s)
Cia2NOD Cia2NOD QTL

Gene(s)
Name Comment Chromosome
collagen induced arthritis QTL 2 not provided yet 2

Handling & Genotyping Instructions
Name Type

Mammalian Phenotype Ontologies
 
MP Term: immune system phenotype>abnormal immune system physiology
PATO Logical Definition:  functionality qualifier abnormal inheres_in immune system process
 

References
Name Type Comment
Johansson et al., 2001 Eur J Immunol 31(6):1847-56 Webblink Genetic control of collagen-induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcgammaRIIb and is not associated with loci controlling diabetes.

Author's Comments